Water intoxication during carbamazepine treatment.

Carbamazepine has recently been shown to have a vasopressin-like action and, like chlorpropamnide, to be effective in controlling polyuria in patients with diabetes insipidus (Hartman, 1972; Uhlich et al., 1972). In the case reported here carbamazepine, which was being given to a patient suffering from depression and psychogenic polydipsia, induced inappropriate secretion of antidiuretic hormone and water intoxication.